Drosophila gene that is required for development of the R7 cell in each ommatidium in the eye. Gene product is a receptor tyrosine kinase, related to the insulin receptor. Ligand is the product of the bride of sevenless gene. In the downstream signalling cascade son-of sevenless plays an important part.

Dictionary of molecular biology. 2004.

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  • sevenless — sevenless. Ген, контролирующий у дрозофилы Drosophila melanogaster развитие седьмой фоторецепторной клетки в составе фасетки сложного глаза, мутации гена sevenless обусловливают развитие конической клетки; считается, что продукт, кодируемый этим… …   Молекулярная биология и генетика. Толковый словарь.

  • sevenless — noun A gene in Drosophila melanogaster that encodes a receptor tyrosine kinase protein essential to the development of R7 cells in the embryonic eye …   Wiktionary

  • Son of Sevenless — protein Name = son of sevenless homolog 1 (Drosophila) caption = width = HGNCid = 11187 Symbol = SOS1 AltSymbols = GINGF EntrezGene = 6654 OMIM = 182530 RefSeq = NM 005633 UniProt = Q07889 PDB = ECnumber = Chromosome = 2 Arm = p Band = 21… …   Wikipedia

  • bride of sevenless — (= boss) In Drosophila eye development, the ligand for the sevenless tyrosine kinase receptor. Boss is expressed by the central R8 cell. It is unusual as a ligand for a tyrosine receptor kinase in that it is on the surface of another cell and has …   Dictionary of molecular biology

  • son-of-sevenless — Drosophila ras GRF (GDF releasing factor), mammalian homologues of which (sos1, sos2) play an important part in intracellular signalling. See sos …   Dictionary of molecular biology

  • SOS1 — Son of sevenless homolog 1 (Drosophila), also known as SOS1, is a human gene. PBB Summary section title = summary text = RAS genes (e.g., MIM 190020) encode membrane bound guanine nucleotide binding proteins that function in the transduction of… …   Wikipedia

  • RhoGEF domain — Structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein.[1] Identifiers Symbol …   Wikipedia

  • Sos — steht für: SOS (Notsignal), ein internationales Notsignal die ISO Abkürzung für Somalia Schilling Seminar für Orientalische Sprachen, eine 1887 gegründete Einrichtung der Universität Berlin Sensor Observation Service, einen Dienst zur Steuerung… …   Deutsch Wikipedia

  • hook — (1) Basal portion of bacterial flagellum, to which is distally attached the flagellin filament. Proximally the hook is attached to the rotating spindle of the motor. In some bacteria (Myxobacteria) the rotation of the hook itself (without an… …   Dictionary of molecular biology

  • Anaphylaxis — Infobox Disease Name = Anaphylaxis Caption = DiseasesDB = 29153 ICD10 = ICD10|T|78|2|t|66 ICD9 = ICDO = OMIM = MedlinePlus = eMedicineSubj = med eMedicineTopic = 128 MeshID = D000707 Anaphylaxis is an acute systemic (multi system) and severe Type …   Wikipedia

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